发明名称 Stabilized aqueous compositions of neuromuscular blocking agents
摘要 <p>The invention relates to an aqueous composition comprising a quaternary ammonium blocking agent and a polyhydroxy acid based excipient, and a method for producing said composition. In particular the neuromuscular blocking agent may be a Rocuronium salt and the excipient is an aldonic acid, e. g. gluconic acid or an intramolecular lactone thereof. Furthermore, the invention relates to a liquid pharmaceutical composition comprising said aqueous composition. The compositions of the present invention can further be comprised in a container made of glass or an organic polymer. Additionally, the invention relates to a pharmaceutical kit comprising the compositions of the present invention.</p>
申请公布号 IL236042(D0) 申请公布日期 2015.01.29
申请号 IL20140236042 申请日期 2014.12.03
申请人 B. BRAUN MELSUNGEN AG 发明人
分类号 A61K 主分类号 A61K
代理机构 代理人
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