BIOTINYLATED MHC COMPLEXES AND THEIR USES

摘要

The invention demonstrates an improved choice of biotinylation peptide to be used in a combination or fusion with an MHC molecule for immobilizing or multimerising such MHC molecules for a variety of purposes.

主权项

1. A chimeric peptide comprising an MHC peptide and a biotinylation peptide which either is a natural biotinylation peptide or has a greater than 70% sequence homology to a natural biotinylation peptide, the biotinylation peptide comprising a minimal sequence from a naturally occurring biotinylation domain that can be biotinylated by a corresponding enzyme.