Preparation and method for producing a preparation comprising mesenchymal stem cells

摘要

Preparation and method for producing a preparation or a tissue derivative that include mesenchymal stem cells, to be used in cellular therapy, for cosmetic treatments, for replacing a tissue or an organ, or inducing or accelerating tissue repair or regeneration. The method includes the steps of extracting tissue containing mesenchymal stem cells, such as adipose tissue, from a cadaveric donor by liposuction or by surgical removal of parts of adipose tissue, and mechanically treating tissue to provide a fluid component, having an oily component, a blood component and/or a sterile solution, and a solid component having cell fragments, cells and one or more cell macro-agglomerates of heterogeneous sizes, thereby separating and removing the fluid component from the solid component, which generates an emulsion of fluid components.

主权项

1. A method of producing a preparation or a tissue derivative comprising mesenchymal stem cells, to be used in cellular therapy, for cosmetic treatments, for replacing a tissue or an organ, or inducing or accelerating tissue repair or regeneration, the method comprising the following steps:
extracting tissue containing mesenchymal stem cells from a cadaveric donor by liposuction process or by surgical removal of parts of said tissue; and mechanically treating said tissue, wherein said mechanically treated tissue includes a fluid component comprising one or more of an oily component, a blood component, or a sterile solution, and a solid component comprising cell fragments, cells and one or more cell macro-agglomerates of heterogeneous sizes, and wherein the steps of mechanically treating separates and removes the fluid component from the solid component, whereby an emulsion of fluid components is generated by mechanical stirring.