发明名称 THIOUREA DERIVATIVE AS GLUTAMINYL CYCLASE INHIBITOR
摘要 PROBLEM TO BE SOLVED: To provide a novel thiourea compound useful as a glutaminyl cyclase inhibitor.SOLUTION: This invention relates to a thiourea compound represented by formula (I), where A is the following formula; B is H or methyl; R, R, and Rare alkyl or the like; and Z is a divalent bond group.
申请公布号 JP2015017107(A) 申请公布日期 2015.01.29
申请号 JP20140179194 申请日期 2014.09.03
申请人 PROBIODRUG AG 发明人 BUCHHOLZ MIRKO;ANDRE J NIESTROJ;HEISER ULRICH;ROBERT SOMMER
分类号 C07D235/08;A61K31/417;A61K31/4184;A61K31/422;A61K31/433;A61K31/454;A61K31/496;A61K31/5377;A61K45/00;A61P1/14;A61P1/18;A61P3/00;A61P3/04;A61P5/00;A61P9/10;A61P15/08;A61P17/06;A61P19/02;A61P25/00;A61P25/02;A61P25/14;A61P25/16;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P25/28;A61P29/00;A61P35/00;A61P35/04;A61P37/02;A61P37/04;A61P43/00;C07D233/61;C07D405/12;C07D409/12;C07D413/12;C07D417/12 主分类号 C07D235/08
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