Driving Patient Compliance with Therapy

摘要

Methods of the invention involve determining a patient's compliance with a cholesterol lowering therapy. In certain aspects, the invention provides methods that involve conducting a first assay to determine a cholesterol biomarker level in a first sample from a patient prior to the patient undergoing a cholesterol lowering therapy. The methods may also involve conducting a second assay to determine a cholesterol level in a second sample obtained from the patient after the patient has started undergoing a cholesterol lowering therapy. Additionally, the methods involve associating the cholesterol level and the cholesterol biomarker level in which the association allows for the determination of the patient's compliance with the cholesterol lowering therapy.

主权项

1. A method for determining a patient's compliance with a cholesterol lowering therapy, the method comprising:
conducting a first assay to determine a level of a cholesterol absorption biomarker and a level of a cholesterol production biomarker in a first sample from a patient obtained at a first time point that is prior to the patient undergoing a cholesterol lowering therapy; conducting a second assay to determine a cholesterol level in a second sample obtained from the patient obtained at a second time point that is after the patient has started undergoing the cholesterol lowering therapy; and associating the cholesterol level obtained at the second time point and the cholesterol absorption and production biomarker levels obtained at the first time point; identifying the patient as compliant or non-compliant with the cholesterol lowering therapy based on the association.