COMBINATION THERAPY FOR TREATING ANDROGEN DEFICIENCY

摘要

The present invention relates to a combination therapy for elevating testosterone levels in male mammals in which an antiestrogen or pharmaceutically acceptable salt thereof is co-administered to the mammal with an additional therapeutic agent selected from an androgen and an aromatase inhibitor. The invention is also directed to a combination therapy for treating males with hypogonadism and disorders related thereto, including reduction of muscle mass. limitation of body performance capacity, reduction of bone density, reduction of libido, reduction of potency, reduction of benign prostatic hyperplasia and infertility.

主权项

1. A method for treating secondary hypogonadism or a disorder associated with secondary hypogonadism in a human male in need thereof, comprising co-administering to the human male an effective amount of an antiestrogen or pharmaceutically acceptable salt thereof and an additional therapeutic agent selected from an androgen and an aromatase inhibitor.