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发明名称
OPTIMIZED Fc VARIANTS
摘要
The present invention relates to Fc variants having decreased affinity for FcγRIIb, methods for their generation, Fc polypeptides comprising optimized Fc variants, and methods for using optimized Fc variants.
申请公布号
US2015030592(A1)
申请公布日期
2015.01.29
申请号
US201414458126
申请日期
2014.08.12
申请人
Xencor, Inc.
发明人
Lazar Gregory;Dang Wei;Desjarlais John;Karki Sher;Vafa Omid;Hayes Robert;Vielmetter Jost
分类号
C07K16/30
主分类号
C07K16/30
代理机构
代理人
主权项
地址
Monrovia CA US
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