发明名称 ROLE OF N-2-HYDROXY-ETHYL-PIPERAZINE-N'-2-ETHANE SULFONATE (HEPES) IN PAIN CONTROL AND REVERSAL OF DEMYELINATION INJURY
摘要 PROBLEM TO BE SOLVED: To provide a pharmaceutical composition for treating withdrawal symptoms, side effects or both after the treatment with anti-depressants, selective serotonin inhibitors (SSRI) or other neurological agents, and to provide a pharmaceutical composition for treating one or more neurodegenerative diseases, one or more demyelination injuries or both, and to provide a pharmaceutical composition for treating pain associated with cancers, side effects after cancer therapy including the post chemical therapy cognitive impairment or both.SOLUTION: Provided is a pharmaceutical composition comprising N-2-hydroxy-ethyl-piperazine-N'-2-ethane sulfonate (HEPES) or a derivative thereof dissolved in sterilized water, a buffer, physiological saline or other pharmaceutically acceptable carrier.
申请公布号 JP2015052006(A) 申请公布日期 2015.03.19
申请号 JP20140231168 申请日期 2014.11.14
申请人 NORTH TEXAS MEDICAL ASSOCIATES 发明人 IVAN E DANHOF
分类号 A61K31/495;A61P25/02;A61P25/04;A61P25/14;A61P25/16;A61P25/24;A61P25/28;A61P35/00;A61P43/00 主分类号 A61K31/495
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