发明名称 Pharmaceutical Composition of Ibuprofen and Tramadol for Ophthalmic Use
摘要 The present invention relates to a pharmaceutical composition of ibuprofen and tramadol for ophthalmic use. Said composition is effective and safe for the treatment of ocular inflammation and/or pain associated to different diseases or pathological states which affect the eye area In particular, the ophthalmic composition of the invention is indicated, for example, for the treatment of pain and/or inflammation after eye surgery.
申请公布号 US2015105468(A1) 申请公布日期 2015.04.16
申请号 US201414511321 申请日期 2014.10.10
申请人 Farmalider, S.A. 发明人 Martinez-Alzamora Fernando;Rizo Martinez Jose Miguel;Gomez Calvo Antonia;Sanz Menendez Nuria;Munoz Ruiz Angel
分类号 A61K31/192;A61K9/00;A61K31/135 主分类号 A61K31/192
代理机构 代理人
主权项 1. An aqueous ophthalmic pharmaceutical composition comprising: a) ibuprofen, or a pharmaceutically acceptable salt thereof, in a concentration of between 0.01% (wlv) and 0.5% (w/v); and b) tramadol, or a pharmaceutically acceptable salt thereof, in a concentration, expressed as equivalent concentration of tramadol hydrochloride, of between 0.05% (w/v) and 2% (w/v).
地址 Alcobendas (Madrid) ES