主权项 |
1. A compound of the formula (I) in which R1 is hydrogen or (C1-C4)-alkyl, R2 is a group of the formula where* is the attachment site to the uracil nitrogen atom,A is —CH2—, —CH2—CH2—, —O—CH2-## or oxygen,
in which## is the attachment site to the phenyl ring,m is a number 0, 1 or 2,R4 is halogen, difluoromethyl, trifluoromethyl, (C1-C4)-alkyl, difluoromethoxy, trifluoromethoxy or (C1-C4)-alkoxy,R5A is hydrogen or deuterium,R5B is hydrogen, deuterium or (C1-C4)-alkyl,R6 is hydrogen or fluorine,R7 is hydrogen or fluorine,R8 is halogen, difluoromethyl, trifluoromethyl, (C1-C4)-alkyl or nitro,R9 is hydrogen, halogen, difluoromethyl, trifluoromethyl, (C1-C4)-alkyl, nitro or (C1-C4)-alkylthio, R3 is a group of the formula where# is the attachment site to the uracil nitrogen atom,the ring Q is 5- to 7-membered heterocyclyl or 5- or 6-membered heteroaryl,
in which 5- to 7-membered heterocyclyl and 5- or 6-membered heteroaryl may be substituted by 1 to 4 substituents independently selected from the group of halogen, difluoromethyl, trifluoromethyl, trideuteromethyl, (C1-C6)-alkyl, (C3-C7)-cycloalkyl, oxo, hydroxyl, (C1-C4)-alkylcarbonyl, (C1-C4)-alkoxycarbonyl, aminocarbonyl and (C1-C4)-alkylsulphonyl,
in which (C1-C6)-alkyl and (C3-C7)-cycloalkyl may in turn be substituted by 1 to 3 substituents independently selected from the group of halogen, cyano, trifluoromethyl, (C3-C7)-cycloalkyl, hydroxyl, (C1-C4)-alkoxy and 4- to 7-membered heterocyclyl, andin which two (C1-C6)-alkyl radicals bonded to a carbon atom of 5- to 7-membered heterocyclyl and 5- or 6-membered heteroaryl, together with the carbon atom to which they are bonded, may form a 3- to 6-membered carbocycle,R24 is halogen, (C1-C4)-alkyl or (C1-C4)-alkoxy,n is a number 0, 1, 2 or 3, and the salts, solvates and solvates of the salts thereof. |