主权项 |
1. Compound of the formula (I) Wherein L stands for a straight-chain (C1-C12)-alkandiyl, which may be substituted with methyl up to four times and in which (a) two carbon atoms may be connected to each other in 1,2-, 1,3- or 1,4 relation, if necessary including carbon atoms that are located between them to form a (C3-C6)-cycloalkyl-ring or a phenyl ring or (b) up to three CH2 groups not adjacent to each other may be substituted for an O, R1 stands for hydrogen or methyl, R2 stands for isopropyl, isobutyl, sec.-butyl, tert.-butyl, 1-hydroxyethyl, phenyl, benzyl, 4-hydroxybenzyl, 1-phenylethyl, diphenylmethyl, 1H-imidazol-4-ylmethyl or 1H-indol-3-ylmethyl, Or R1 and R2, together with the carbon atom to which they are both connected, form a 2-phenylcyclopropan-1,1-diyl group of the formula Wherein
# marks the points of attachment with other parts of the molecule, And T stands for a group with formula —C(═O)—OR3, —C(═O)—NR4R5, —C(═O)—NH—NH—R6 or —CH2—O—R7 in which
R3 stands for hydrogen, (C1-C6)-alkyl or (C3-C10)-cycloalkyl,
wherein (C1-C6)-alkyl may be substituted with phenyl, naphthyl or (C3-C10)-cycloalkyl,R4 stands for hydrogen or (C1-C6)-alkyl,R5 stands for hydrogen, (C1-C6)-alkyl or (C3-C10)-cycloalkyl,
wherein (C1-C6)-alkyl may be substituted with phenyl,OrR4 and R5 are connected to each other and, together with the nitrogen atom they are attached to, form a 5- to 7-membered, saturated aza-heterocyclic compound, which may contain a further ring-heteroatom such as >N—H, >N—CH3 or —O—; and is located either at the 1,3- or 1,4-location in relation to the aforementioned nitrogen atom,R6 stands for (C1-C6)-alkyl, (C1-C6)-alkylcarbonyl, phenyl or benzoyl, andR7 stands for (C1-C6)-alkyl, which may be substituted with phenyl,
Where phenyl may also be substituted with (C1-C6)-alkoxycarbonyl or carboxyl, and also their salts, solvates and solvates of the salts. |