METHOD AND COMPOSITION RELATED TO ANNEXIN 1-BINDING COMPOUND

摘要

PROBLEM TO BE SOLVED: To provide methods and compositions related to annexin 1-binding compounds.SOLUTION: There are provided conjugates comprising the annexin 1-binding peptide IFLLWQR covalently linked to a therapeutic or detectable agent. Also disclosed are compositions comprising a moiety and a peptide comprising an amino acid sequence that can bind to a carbohydrate receptor on a cell. Also disclosed are isolated nucleic acids comprising a nucleic acid sequence encoding a peptide comprising an amino acid sequence that can bind to a carbohydrate receptor on a cell. Also disclosed are methods comprising the step of administering to a subject a composition comprising a moiety and a peptide comprising an amino acid sequence that can bind to a carbohydrate receptor on a cell. Also disclosed are methods of targeting a tumor cell in a subject comprising the step of administering to the subject a peptide comprising an amino acid sequence that can bind to a carbohydrate receptor on a cell.