摘要 |
The present invention refers to new classes of polymerisable monomers targeting biotin, a biotin derivative, a biotin analogue or a biotinylated molecule and related structures, as well as molecularly imprinted polymers obtainable by polymerisation of at least one of these monomers and at least one cross-linking monomer in the presence of a suitable template molecule. The obtained polymers may be used for separation of biotin and related small molecules, together with larger biotinylated molecules of biological origin, e.g. proteins, from complex mixtures. The monomer comprises i) an isophthalic acid derivative or a pyridine-2,6-dicarboxylic acid derivative and ii) a vinyl-2-aminopyridine derivative |