| 摘要 |
The present invention relates to pharmaceutical compositions containing a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide including formulations of the solid dispersions into powders, granules and mini-tablets, methods for manufacturing and processing the powders, granules and mini-tablets, and methods for treating cystic fibrosis employing the pharmaceutical composition. |
| 申请人 |
VERTEX PHARMACEUTICALS INCORPORATED |
发明人 |
DOKOU, ELENI E;JAMZAD, SHAHLA S;CAESAR, JOHN, P., JR. JP;FAWAZ, MAJED M;DAS, LAURA L;GU, CHONG-HUI C-H;HURTER, PATRICIA, NELL PN;ISRANI, MEGHNA, JAI MJ;JOHNSTON, MEGHAN, M. MM;KNEZIC, DRAGUTIN D;KUZMISSION, ANDREW, G. AG;WANG,HONGREN H |
