| 发明名称 |
COMPOSITION COMPRISING AN ENCAPSULATED ANTAGOMIR |
| 摘要 |
The invention relates to a composition comprising an effective amount of at least one inhibitor of a miRNA involved in the angiogenesis, or a precursor thereof, wherein said inhibitor is microencapsulated into polymeric biodegradable and biocompatible microspheres. The invention also relates to the use of the said composition for preventing or treating cardiac disorders, including cardiac disorders caused by ischemy. |
| 申请公布号 |
US2015352055(A1) |
申请公布日期 |
2015.12.10 |
| 申请号 |
US201414763181 |
申请日期 |
2014.01.23 |
| 申请人 |
PIERRE FABRE MEDICAMENT S.A.S. ;FUNDACIO HOSPITAL UNIVERSITARI VALL D'HEBRON - INSTITUT DE RECERCA |
发明人 |
ASIN Miguel-Angel;FERRET Eulalia;PEREZ Amadeo;GOTARDA Neus Bellera;RODRIGUEZ SINOVAS Antonio;VERT Ignasi Barba;GARCIA-DORAD GARCIA Antonio David |
| 分类号 |
A61K9/50;C12N15/113 |
主分类号 |
A61K9/50 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. Composition comprising an effective amount of at least one inhibitor of a miRNA involved in angiogenesis, or a precursor thereof, wherein said inhibitor or said precursor thereof is microencapsulated into polymeric biodegradable and biocompatible microspheres. |
| 地址 |
Boulogne Cedex FR |
