| 摘要 |
<p>Disclosed are effective oral contraceptive regimens comprising an antiprogestogen phase combined with a progestogenic phase. A contraceptive regimen having: a first phase of 5-20, especially 14, sequential daily dosage units containing an anti-progestogen at a daily dosage sufficient to inhibit ovulation in the female, and a second phase of 10 to 25, especially 14, sequential daily dosage units containing a progestogen at a dosage equivalent to 40-120 νg desogestrel administered orally. To the first phase is preferentially added an estrogen such as 17β-estradiol (from 0.50 to 2.5 mg daily) to allow for the possibility of making a sequential regimen. The invention also includes a contraceptive product (i.e. the package containing the dosage unit regimen), and a process of manufacturing this product.</p> |
