发明名称 PEPTIDE HAVING INFLAMMATION AFFINITY AND RADIOACTIVE DIAGNOSTIC CONTAINING THE SAME
摘要 A peptide having affinity with inflammation is disclosed, which contains at least one of the following amino acid sequences: <IMG> , and <IMG> , wherein A, C, E, G, I, K, L, N, P, Q, R, 5, T, V, and Y represent amino acid residues expressed by standard one-letter symbols, According to the present invention, a peptide and its chemically modified substances, radioactive metal labeled peptides derived therefrom, and radioactive diagnostics comprising such peptide are provided, which are useful for imaging inflammation region and easy in preparation handling, and accumulate at inflammation site immediately after administration while being excellent in clearance into urine. The imaging is possible in several ten minutes after administration.
申请公布号 CA2134051(A1) 申请公布日期 1995.04.23
申请号 CA19942134051 申请日期 1994.10.21
申请人 NIHON MEDI-PHYSICS CO., LTD. 发明人 ITAYA, YOSHITOSHI;HANAOKA, KOICHI;SHIRAKAMI, YOSHIFUMI
分类号 A61K51/08;A61K51/10;C07K16/00;(IPC1-7):C07K14/00;A61K49/02;C07K7/04;C07K17/08;C07K17/10;C07K1/13 主分类号 A61K51/08
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