摘要 |
A peptide having affinity with inflammation is disclosed, which contains at least one of the following amino acid sequences: <IMG> , and <IMG> , wherein A, C, E, G, I, K, L, N, P, Q, R, 5, T, V, and Y represent amino acid residues expressed by standard one-letter symbols, According to the present invention, a peptide and its chemically modified substances, radioactive metal labeled peptides derived therefrom, and radioactive diagnostics comprising such peptide are provided, which are useful for imaging inflammation region and easy in preparation handling, and accumulate at inflammation site immediately after administration while being excellent in clearance into urine. The imaging is possible in several ten minutes after administration.
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