发明名称 STABILIZED ERYTHROPOIETIN AQUEOUS SOLUTION
摘要 FIELD: medicine, pharmacy. SUBSTANCE: invention proposes aqueous solution containing erythropoietin at concentration 500-4000 IU/1 ml, dextran of molecular mass 30000-60000 Da at concentration 6-10 wt.-%, sodium citrate and citric acid to obtain isotonicity and pH value of solution 6.5-7.5. Solution can contain additionally 5 wt.-% of mannitol or glucose. Invention provides to get useful life of solution up to 2 years under storage conditions at 2-8 C. Obtained stable erythropoietin solution can be used for treatment of patients with anemia. EFFECT: enhanced efficiency. 3 cl, 2 dwg, 1 tbl, 5 ex
申请公布号 RU2128517(C1) 申请公布日期 1999.04.10
申请号 RU19980113165 申请日期 1998.07.20
申请人 KOLOBKOV SERGEJ LEONIDOVICH;KUROCHKIN SERGEJ NIKOLAEVICH;SEROV SERGEJ MIKHAJLOVICH 发明人
分类号 A61K38/22;A61K9/08;A61K47/02;A61K47/12;A61K47/26 主分类号 A61K38/22
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