发明名称 NOVEL MULTISPECIFIC CONSTRUCTS
摘要 Provided are novel multispecific antibody constructs and multispecific antibody drug conjugates (ADCs), and methods of using such antibodies and ADCs to treat cancer. IgG-like bispecific antibodies have different binding specificities on each arm of the antibody. They are similar in structure to monospecific IgGs in that they contain two heavy chains with VH, CH1, CH2 and CH3 regions, and two light chains with VL and CL regions.
申请公布号 EP2954056(A1) 申请公布日期 2015.12.16
申请号 EP20140749020 申请日期 2014.02.07
申请人 STEMCENTRX, INC. 发明人 LIU, DAVID
分类号 C12N15/13;C07K16/28;C07K16/46 主分类号 C12N15/13
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