发明名称 |
A PROTEIN-INDUCED PLURIPOTENT CELL TECHNOLOGY USES THEREOF |
摘要 |
<p>A method of generating protein-induced pluripotent stem cells by delivering bacterially expressed reprogramming proteins into nuclei of starting somatic cells using the QQ-protein transduction technique, repeating several cell reprogramming cycles for creating reprogrammed protein-induced pluripotent stem cells, moving the reprogrammed cells into a feeder-free medium for expansion, and expanding and passaging the reprogrammed cells in a whole dish for generating homogeneous piPS cells. Also provided are the piPCS cells formed using this method and uses thereof.</p> |
申请公布号 |
EP2705143(A4) |
申请公布日期 |
2015.12.16 |
申请号 |
EP20120779306 |
申请日期 |
2012.05.02 |
申请人 |
WAYNE STATE UNIVERSITY |
发明人 |
WANG, JIANJUN;LI, QIANQIAN |
分类号 |
A01N63/00;C12N5/00;C12N5/071 |
主分类号 |
A01N63/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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