| 发明名称 | Trio-based phasing using a dynamic Bayesian network | ||
| 摘要 | Performing trio-based phasing includes: obtaining a set of preliminary phased haplotype data of an individual; establishing a dynamic Bayesian network based at least in part on the set of preliminary phased haplotype data of the individual and phased haplotype data of at least one parent of the individual; and determining, based on the dynamic Bayesian network, a set of refined haplotype data of the individual. | ||
| 申请公布号 | US9213944(B1) | 申请公布日期 | 2015.12.15 |
| 申请号 | US201313801552 | 申请日期 | 2013.03.13 |
| 申请人 | 23andMe, Inc. | 发明人 | Do Chuong;Durand Eric;Macpherson John Michael |
| 分类号 | G06F17/00;G06N5/02;G06N7/00 | 主分类号 | G06F17/00 |
| 代理机构 | Van Pelt, Yi & James LLP | 代理人 | Van Pelt, Yi & James LLP |
| 主权项 | 1. A system for performing trio-based phasing, comprising: one or more processors configured to: obtain a set of preliminary phased haplotype data of an individual;establish a dynamic Bayesian network based at least in part on the set of preliminary phased haplotype data of the individual and phased haplotype data of at least one parent of the individual; anddetermine, based on the dynamic Bayesian network, a set of refined haplotype data of the individual; and one or more memories coupled with the one or more processors, configured to provide the one or more processors with instructions. | ||
| 地址 | Mountain View CA US | ||