| 发明名称 | Collagenase G and Collagenase H compositions for the treatment of diseases involving alterations of collagen | ||
| 摘要 | Compositions comprising collagenase G and collagenase H (in a ratio between 1:2.5 and 1:3.5), optionally formulated in hydrogels, and its uses as medicament for the treatment of diseases involving alterations of collagen, such as fibromatosis, palmar Dupuytren's contracture, La Peyronie's disease, Ledderhose's disease or retractable scars. | ||
| 申请公布号 | US9211316(B2) | 申请公布日期 | 2015.12.15 |
| 申请号 | US201113876674 | 申请日期 | 2011.09.30 |
| 申请人 | PROTEOS BIOTECH S.L.U. | 发明人 | Muñoz Montano Juan Ramón |
| 分类号 | A61K38/46;C12N9/50;A61K38/48;A61K9/00;A61K9/06;A61K9/19;A61K47/36 | 主分类号 | A61K38/46 |
| 代理机构 | Moore & Van Allen, PLLC | 代理人 | Fuierer Tristan A.;Moore & Van Allen, PLLC |
| 主权项 | 1. A composition comprising recombinant Collagenase G and recombinant Collagenase H having a mass ratio between 1:2.5 and 1:3.5, wherein the recombinant Collagenase G has the amino acid sequence of SEQ ID NO: 1 and the recombinant Collagenase H has the amino acid sequence SEQ ID NO: 2. | ||
| 地址 | Albacete ES | ||