发明名称 Organic metal complex and process for preparing amine compound
摘要 [Problem];The present invention aims to provide a novel organometallic compound that can be used as a general-use highly active catalyst with superior selectivity for functional groups.;[Means for Solving Problem];The present invention relates to an organometallic compound having a novel specific structure of general formula (1):; and to a general-use highly active catalyst used in reductive amination reaction with superior selectivity for functional groups that comprises said organometallic compound, and to a process for preparing amine compounds by reductive amination reaction using said catalyst.
申请公布号 US9211533(B2) 申请公布日期 2015.12.15
申请号 US201313911188 申请日期 2013.06.06
申请人 Kanto Kagaku Kabushiki Kaisha 发明人 Watanabe Masahito;Hori Junichi;Murata Kunihiko
分类号 C07F15/00;B01J31/12;B01J31/22;C07C209/78 主分类号 C07F15/00
代理机构 Wolf, Greenfield & Sacks, P.C. 代理人 Wolf, Greenfield & Sacks, P.C.
主权项 1. An organometallic compound of general formula (3): (wherein in general formula (3), Ar is a cyclopentadienyl group in which one or more hydrogen atoms may be substituted by a substituent W, and W denotes a saturated or unsaturated C1-10 hydrocarbon group, an aryl group, a heterocyclyl group, an alkoxy group, a fluoroalkyl group, an acyl group, an ester group, a hydroxyl group, an amino group, an amide group, a carboxyl group, a sulfonyl group, a nitro group, a cyano group, a sulfenyl group, a sulfo group, a thiol group, a silyl group or a halogen group, M is rhodium, or iridium, X is a hydride group or an anionic group, each R2 and each R3 independently denote a hydrogen atom, a halogen atom, a nitro group, a cyano group, a hydroxyl group, a sulfo group, a thiol group, a carboxyl group, or the following groups in which one or more hydrogen atoms may be substituted by a substituent W: a C1-10 alkyl group, a cycloalkyl group, an aryl group, a heterocyclyl group, an alkenyl group, an alkynyl group, an alkoxy group, an ester group, a fluoroalkyl group, an acyl group, a sulfonyl group, an amino group, an amide group, an sulfenyl group, or a silyl group, j and k are, independently of one another, an integer from 0 to 3, wherein one or more of carbon atoms, which is(are) not bonded to R2 or R3, in the quinoline ring structure may be replaced with a nitrogen atom, and wherein when j and/or k is(are) 2 or more, 2 or more of R2 and/or R3 may be linked each other to form (a) ring(s)).
地址 Tokyo JP