发明名称 |
Methods and devices for using isoperillyl alcohol |
摘要 |
The present invention provides for a method of treating a disease such as cancer, comprising the step of administering to a patient a therapeutically effective amount of an isomer or analog of monoterpene or sesquiterpene (or its derivative), such as an isoperillyl alcohol. The present invention also provides for a method of treating a disease comprising the step of administering to a patient a therapeutically effective amount of a derivative of an isomer or analog of monoterpene or sesquiterpene, such as an isoperillyl alcohol carbamate. The derivative may be an isoperillyl alcohol conjugated with a therapeutic agent such as a chemotherapeutic agent. The route of administration may vary, including inhalation, intranasal, oral, transdermal, intravenous, subcutaneous or intramuscular injection. |
申请公布号 |
US9211269(B2) |
申请公布日期 |
2015.12.15 |
申请号 |
US201113993910 |
申请日期 |
2011.12.16 |
申请人 |
NEONC TECHNOLOGIES INC. |
发明人 |
Chen Thomas;Levin Daniel;Pupalli Satish;Dickman Daniel A |
分类号 |
C07C35/18;A61K31/045;A61P35/00;A61K31/05;A61K45/06;A61K31/165;A61K47/48;A61K31/415;A61K31/4188;A61K31/4015;A61K31/325 |
主分类号 |
C07C35/18 |
代理机构 |
Ascenda Law Group PC |
代理人 |
Ascenda Law Group PC |
主权项 |
1. A method for killing malignant glioma cells, comprising treating the malignant glioma cells with an amount of (4-isopropylidene cyclohex-1-enyl)methanol, wherein the amount of (4-isopropylidene c clohex-1-eny l)methanol is less than the amount of perillyl alcohol needed to achieve the same level of killing. |
地址 |
Los Angeles CA US |