发明名称 Methods and devices for using isoperillyl alcohol
摘要 The present invention provides for a method of treating a disease such as cancer, comprising the step of administering to a patient a therapeutically effective amount of an isomer or analog of monoterpene or sesquiterpene (or its derivative), such as an isoperillyl alcohol. The present invention also provides for a method of treating a disease comprising the step of administering to a patient a therapeutically effective amount of a derivative of an isomer or analog of monoterpene or sesquiterpene, such as an isoperillyl alcohol carbamate. The derivative may be an isoperillyl alcohol conjugated with a therapeutic agent such as a chemotherapeutic agent. The route of administration may vary, including inhalation, intranasal, oral, transdermal, intravenous, subcutaneous or intramuscular injection.
申请公布号 US9211269(B2) 申请公布日期 2015.12.15
申请号 US201113993910 申请日期 2011.12.16
申请人 NEONC TECHNOLOGIES INC. 发明人 Chen Thomas;Levin Daniel;Pupalli Satish;Dickman Daniel A
分类号 C07C35/18;A61K31/045;A61P35/00;A61K31/05;A61K45/06;A61K31/165;A61K47/48;A61K31/415;A61K31/4188;A61K31/4015;A61K31/325 主分类号 C07C35/18
代理机构 Ascenda Law Group PC 代理人 Ascenda Law Group PC
主权项 1. A method for killing malignant glioma cells, comprising treating the malignant glioma cells with an amount of (4-isopropylidene cyclohex-1-enyl)methanol, wherein the amount of (4-isopropylidene c clohex-1-eny l)methanol is less than the amount of perillyl alcohol needed to achieve the same level of killing.
地址 Los Angeles CA US