| 发明名称 | Tablets comprising a taste masking agent | ||
| 摘要 | The present invention is directed to a tablet comprising at least one bitter tasting and/or mucosa numbness causing pharmaceutically active compound; and at least one zinc salt. In addition, the present invention relates to the use of a zinc salt to reduce or mask the bitter taste of or the numbness of the mucosa caused by pharmaceutically active compounds. | ||
| 申请公布号 | US9211265(B2) | 申请公布日期 | 2015.12.15 |
| 申请号 | US201013393779 | 申请日期 | 2010.04.12 |
| 申请人 | HEXAL AG | 发明人 | Storm Klaus |
| 分类号 | A61K31/445;A61K9/70;A61K9/00;A61K9/20 | 主分类号 | A61K31/445 |
| 代理机构 | Arent Fox LLP | 代理人 | Arent Fox LLP |
| 主权项 | 1. A method of reducing or masking the bitter taste of one or more pharmaceutically active compounds provided in an oral solid dosage form comprising: providing a pharmaceutical composition comprising one or more pharmaceutically active compounds having a bitter taste; and adding at least one zinc salt to mask the bitter taste of the one or more pharmaceutically active compounds in the pharmaceutical composition, wherein the ratio of the one or more pharmaceutically active compounds having a bitter taste to the at least one zinc salt is from 2:1 to 5:1 by weight. | ||
| 地址 | Holzkirchen DE | ||