发明名称 |
Method, composition and package for bowel cleansing |
摘要 |
The present invention provides a highly palatable colon cleansing formulation that utilizes a low chloride electrolyte-replenishing base solution. When formulated with polyethylene glycol and a selected sugar alcohol, the formulation offers the advantages of superior palatability without undesirable concomitant side effects or a decrease in cleansing efficacy. |
申请公布号 |
US9211337(B2) |
申请公布日期 |
2015.12.15 |
申请号 |
US201414219468 |
申请日期 |
2014.03.19 |
申请人 |
Braintree Laboratories, Inc. |
发明人 |
Shaver William A. |
分类号 |
A61K35/38;A61K33/14;A61K47/10;A61K9/00;A61K33/00;A61K45/06 |
主分类号 |
A61K35/38 |
代理机构 |
McCarter & English, LLP |
代理人 |
McCarter & English, LLP ;Zacharakis Maria Laccotripe;Gulati Maneesh |
主权项 |
1. A dry composition comprising:
a) between about 0.15-1.5 grams of potassium bicarbonate per liter of colon cleansing solution; b) between about 1.0-3.5 grams of sodium bicarbonate per liter of colon cleansing solution; c) between about 1.0-4.0 grams of citric acid per liter of colon cleansing solution; d) between about 0.1-1.0 grams of sodium chloride per liter of colon cleansing solution; e) between about 50-140.0 grams of polyethylene glycol per liter of colon cleansing solution; and f) between about 1.0-50.0 grams of a sugar alcohol selected from the group consisting of xylitol, erythritol, ribitol, arabitol and mixtures thereof per liter of colon cleansing solution; wherein the dry composition upon reconstitution in an aqueous diluent produces an electrolyte replenishing colon cleansing solution. |
地址 |
Braintree MA US |