发明名称 Method, composition and package for bowel cleansing
摘要 The present invention provides a highly palatable colon cleansing formulation that utilizes a low chloride electrolyte-replenishing base solution. When formulated with polyethylene glycol and a selected sugar alcohol, the formulation offers the advantages of superior palatability without undesirable concomitant side effects or a decrease in cleansing efficacy.
申请公布号 US9211337(B2) 申请公布日期 2015.12.15
申请号 US201414219468 申请日期 2014.03.19
申请人 Braintree Laboratories, Inc. 发明人 Shaver William A.
分类号 A61K35/38;A61K33/14;A61K47/10;A61K9/00;A61K33/00;A61K45/06 主分类号 A61K35/38
代理机构 McCarter & English, LLP 代理人 McCarter & English, LLP ;Zacharakis Maria Laccotripe;Gulati Maneesh
主权项 1. A dry composition comprising: a) between about 0.15-1.5 grams of potassium bicarbonate per liter of colon cleansing solution; b) between about 1.0-3.5 grams of sodium bicarbonate per liter of colon cleansing solution; c) between about 1.0-4.0 grams of citric acid per liter of colon cleansing solution; d) between about 0.1-1.0 grams of sodium chloride per liter of colon cleansing solution; e) between about 50-140.0 grams of polyethylene glycol per liter of colon cleansing solution; and f) between about 1.0-50.0 grams of a sugar alcohol selected from the group consisting of xylitol, erythritol, ribitol, arabitol and mixtures thereof per liter of colon cleansing solution; wherein the dry composition upon reconstitution in an aqueous diluent produces an electrolyte replenishing colon cleansing solution.
地址 Braintree MA US