| 发明名称 |
Modulation of LRCH4 activity and therapeutic application thereof |
| 摘要 |
Disclosed herein are methods for altering cellular functions and processes by modulating the activity of Lrch4. Corresponding compositions that may be used in carrying out the described methods are also disclosed as are related methods of treatment for relevant diseases and physiological states. |
| 申请公布号 |
US9211302(B2) |
申请公布日期 |
2015.12.15 |
| 申请号 |
US201213980097 |
申请日期 |
2012.01.17 |
| 申请人 |
The United States of America, as represented by the Secretary, Department of Health and Human Services |
发明人 |
Fessler Michael B.;Aloor Jim J. |
| 分类号 |
A61K31/713;C12N15/113;A61K38/17;A61K39/395 |
主分类号 |
A61K31/713 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of reducing inflammation in a subject comprising reducing the expression of Lrch4 in the subject by administering a Lrch4-specific oligonucleotide to the subject. |
| 地址 |
Washington DC US |
