发明名称 MEDICINAL EFFECT EVALUATION METHOD OF CRUDE DRUG HAVING HYPOGLYCEMIC ACTION, QUALITY MANAGEMENT METHOD USING THE MEDICINAL EFFECT EVALUATION METHOD, AND MANUFACTURING METHOD
摘要 PROBLEM TO BE SOLVED: To provide a medicinal effect evaluation method of a crude drug and a medicinal effect evaluation method between lots of crude drug which are more inexpensive, simple, has satisfactory repeatability than conventional methods, and to provide a preparation method of an evaluation sample for evaluating the medicinal effect.SOLUTION: A medicinal effect evaluation method between lots of a crude drug having a hypoglycemic action includes: (a) a process of obtaining an extracted fraction for performing medicinal effect evaluation of the crude drug by a method including a process of, after extracting the crude drug by hot water, precipitating obtained hot water extracted fraction by ethanol; (b) a process of making a silkworm to ingest sugar (A) to increase the concentration of sugar (B) in a fat body or in biological fluid of the silkworm; (c) a process of administering the extracted fraction of the crude drug, which was obtained in the process (a), to the silkworm whose concentration of sugar (B) in a fat body or in biological fluid increased, which was obtained in the process (b); and (d) a process of measuring the concentration of sugar (B) in a fat body or in biological fluid of the silkworm to which the extracted fraction of the crude drug was administered.
申请公布号 JP2015224950(A) 申请公布日期 2015.12.14
申请号 JP20140109637 申请日期 2014.05.28
申请人 GENOME SOYAKU KENKYUSHO:KK;UNIV OF TOKYO 发明人 SEKIMIZU KAZUHISA;MATSUMOTO YASUHIKO
分类号 G01N33/50;A61K36/00;A61P3/10;G01N33/66 主分类号 G01N33/50
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