| 发明名称 |
Viral vectors having enhanced effectiveness with reduced virulence |
| 摘要 |
The present invention provides methods of use of recombinant vaccinia virus from which the region encoding the N-terminal 83 or 54 amino acids of the E3L gene product has been deleted, or amino acids at positions 44 and 66 have been mutated. Compositions comprising the recombinant vaccinia virus are also provided.
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| 申请公布号 |
US2002110565(A1) |
申请公布日期 |
2002.08.15 |
| 申请号 |
US20010887295 |
申请日期 |
2001.06.22 |
| 申请人 |
JACOBS BERTRAM;BRANDT TERESA A. |
发明人 |
JACOBS BERTRAM;BRANDT TERESA A. |
| 分类号 |
A61K39/00;A61K39/285;A61K48/00;C12N15/863;(IPC1-7):A61K48/00;A61K39/12;C12N15/86;C12N7/00;A01N63/00;A61K39/275;C12N7/01;C12N15/00;C12N15/09;C12N15/63;C12N15/70;C12N15/74 |
主分类号 |
A61K39/00 |
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