| 发明名称 |
METHOD FOR MAKING 3-HYDROXY, 3- METHYL-5-PREGNAN-20-ONE (GANAXOLONE) 3-3--5--20-() |
| 摘要 |
Applicants have discovered a method for the stereoselective and regioselective synthesis of 3α-hydroxy, 3&bgr;-methyl-5α-pregnan-20-one (ganaxolone) comprising reacting 5α-pregnane-3,20-dione; with an organometallic methylating agent in an inert solvent to provide a compound of the formula |
| 申请公布号 |
HK1171761(A1) |
申请公布日期 |
2015.12.11 |
| 申请号 |
HK20120112640 |
申请日期 |
2012.12.07 |
| 申请人 |
MARINUS PHARMACEUTICALS INC. |
发明人 |
SHAW, KENNETH;HUTCHISON, ALAN |
| 分类号 |
C07J;A61K;A61P |
主分类号 |
C07J |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
