| 摘要 |
FIELD: veterinary virology, biotechnology. ^ SUBSTANCE: claimed vaccine contains antigenic material from virus strain of bird infectious bursal disease (IBD), ethylene imine as inactivation agent; aluminum hydroxide and saponin as adjuvant in effective ratio. Claimed strain is reproduced on 9-11-days embryos of SPF-hens with infective activity of 5.25-7.0 lg EID50/0.2 cm 3. Vaccine represents rose-brown liquid and is administered to healthy bird being 110-120 days old in volume of 0.5 cm2, in single dose. Vaccine of present invention induces high levels of antibodies against IBD of parent bevy and provides anchored passive immunity in 15-25-day young birds. ^ EFFECT: safe vaccine against bird infectious bursal disease. ^ 13 cl, 5 tbl, 6 ex |
