METHOD AND DEVICE FOR SEPARATING METABOLITES OR STEREOISOMERS BY ION MOBILITY SPECTROMETRY

摘要

A method of quantifying the amount of at least two analytes Al and A2 comprised in a sample, comprising: • (a) adding at least one salt (S) to at least a portion (PI) of the sample comprising the at least two analytes Al and A2, • (b) ionizing at least a portion of the sample according to (a) thereby forming an analyte flow comprising the analytes Al and A2 in ionized form, • (c) separating the ionized analytes Al and A2 from each other by using at least one ion mobility separator (124), wherein the analyte flow according to (b) at least partially passes through the ion mobility separator (124), • (d) quantifying the amount of the separated ionized analytes obtained according to (c).