Pharmaceutical Composition for Treating Headache, and Preparation Method Thereof

摘要

A pharmaceutical composition for treating headache, prepared from eleven Chinese herbal medicines: Chinese angelica root, ligusticum chuanxiong, radix paeoniae lactiflorae, prepared rhizome of rehmannia, uncaria tomentosa, leatherleaf milletia, prunella vulgaris, sicklesenna seed, pearl shell, corydalis tuber, and asarum, and a proper amount of adjuvant materials. A preparation method of the pharmaceutical composition, and uses thereof in the preparation of drugs for treating various headaches, traumatic cranial nerve syndrome, dizziness and vertigo, vexation and irritability, insomnia and dreaminess.

主权项

1. A pharmaceutical composition for treatment of headache comprising 4-9 weight parts of Radix Angelicae Sinensis, 4-9 weight parts of Rhizoma Chuanxiong, 2-8 weight parts of Radix Paeoniae alba, 2-8 weight parts of Radix Rehmanniae Preparata, 10-15 weight parts of Ramulus Uncariae cum Uncis, 10-15 weight parts of Caulis Spatholobi, 10-15 weight parts of Spica Prunellae, 10-15 weight parts of Semen Cassiae, 10-15 weight parts of Concha Margaritifera Usta, 4-9 weight parts of Rhizoma Corydalis and 0.5-2 weight parts of Herba Asari, characterized in that said composition is prepared by a method as follows:
a). preparation of #1 Extract: Radix Angelicae Sinensis, Rhizoma Chuanxiong, Rhizoma Corydalis and Semen Cassiae are mixed, extracted by using heating refluxing with ethanol, and filtered to remove impurities; and the ethanol is recovered and concentrated to give #1 Extract for later use; b). preparation of #2 Extract: Radix Paeoniae alba is extracted by using heating refluxing with ethanol, and filtered; and the ethanol is recovered and concentrated to give #2 Extract for later use; c). preparation of #3 Extract: Radix Rehmanniae Preparata, Ramulus Uncariae cum Uncis, Caulis Spatholobi, Spica Prunellae, Concha Margaritifera Usta and Herba Asari are mixed, decocted with water, filtered, concentrated, into which ethanol is added to leave it to stand still, and filtered; and the ethanol is recovered and concentrated to give #3 Extract for later use; d). preparation of formulations: aforesaid three Extracts are added with appropriate amount of excipients, dried, and granulated to obtain the final product.