发明名称 |
CELL CONSTRUCT FOR CELL TRANSPLANTATION, BIOCOMPATIBLE POLYMER BLOCK, AND METHOD FOR PRODUCING THE SAME |
摘要 |
It is an object of the present invention to provide a cell construct for cell transplantation that does not contain a substance having cytotoxicity, such as glutaraldehyde, and suppresses the necrosis of the transplanted cells in the construct (namely, having a high cell survival rate). The present invention provides a cell construct for cell transplantation comprising biocompatible polymer blocks that do not contain glutaraldehyde and at least one type of cells, wherein a plurality of biocompatible polymer blocks are disposed in gaps among a plurality of cells, and wherein the biocompatible polymer blocks have a tap density of 10 mg/cm3 or more and 500 mg/cm3 or less, or the value of the square root of the cross-sectional area/boundary length in the two-dimensional sectional image of the polymer block is 0.01 or more and 0.13 or less. |
申请公布号 |
US2015352252(A1) |
申请公布日期 |
2015.12.10 |
申请号 |
US201514836504 |
申请日期 |
2015.08.26 |
申请人 |
FUJIFILM CORPORATION |
发明人 |
NAKAMURA Kentaro;IWAZAWA Reiko;MIYOSHI Hayato;YAMAGUCHI Kazuhiro;FUSHIMI Hideo |
分类号 |
A61L27/22;A61L27/38;A61L27/36 |
主分类号 |
A61L27/22 |
代理机构 |
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代理人 |
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主权项 |
1. A cell construct for cell transplantation comprising biocompatible polymer blocks that do not contain glutaraldehyde and at least one type of cells, wherein a plurality of biocompatible polymer blocks are disposed in gaps among a plurality of cells, and wherein the biocompatible polymer blocks have a tap density of 10 mg/cm3 or more and 500 mg/cm3 or less, or the value of the square root of the cross-sectional area/boundary length in the two-dimensional sectional image of the polymer block is 0.01 or more and 0.13 or less. |
地址 |
Tokyo JP |