DATA INDEPENDENT ACQUISITION OF PRODUCT ION SPECTRA AND REFERENCE SPECTRA LIBRARY MATCHING

摘要

PROBLEM TO BE SOLVED: To provide data independent acquisition of product ion spectra and reference spectra library matching.SOLUTION: A system and a method are used to store an electronic record of whole product ion spectra of whole detectable compounds of a sample. A plurality of product ion scans are performed one or more times on a tandem mass spectrometer using a plurality of mass selection windows in a single sample analysis across a mass range of the sample. The whole sample product ion spectra of the whole detectable compounds for each mass selection window are produced. The whole sample product ion spectra for each mass selection window are received from the tandem mass spectrometer using a processor. The whole sample product ion spectra for each mass selection window are stored as an electronic record of the whole detectable compounds of the sample using the processor. The electronic record is used to characterize compounds known at the time when the electronic record is stored or to characterize compounds that are known after the electronic record is stored.