COMPOSITIONS CONTAINING SIMVASTATIN IN OMEGA-3 POLYUNSATURATED FATTY ACIDS

摘要

The present application relates to compositions comprising simvastatin, omega-3 polyunsaturated fatty acids (n-3 PUFA), or their alkyl esters, and a ionic solvent selected between sodium docusate and a phosphatidylcholine-enriched lechitin, wherein the recovery of simvastatin is at least 95% after 6 months at 40°C. The pharmaceutical composition according to the present invention can be used in the prevention and treatment of hyperlipidemia, hypercholesterolemia, hypertriglyceridemia and all the pathologies related.