MITOCHONDRIAL PREPROTEINS AS MARKERS FOR ALZHEIMER'S DISEASE
摘要
<p>The present invention is inter alia concerned with a method of diagnosing Alzheimer's disease in a patient, wherein said method is based on determining the amount of at least one premature mitochondrial protein. Further, the present invention relates to the use of such a protein as marker for Alzheimer's disease. Accordingly, antibodies binding to such a preprotein may be used for diagnosing Alzheimer's disease. The present invention is based on the finding that prematuremitochondrial proteins accumulate in Alzheimer's disease.</p>
申请公布号
WO2015132397(A3)
申请公布日期
2015.12.10
申请号
WO2015EP54757
申请日期
2015.03.06
申请人
ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG
发明人
MEISINGER, CHRIS;VÖGTLE, NORA;MOSSMANN, DIRK;GLASER, ELZBIETA;GRAFF, CAROLINE;ZAHEDI, RENÉ, P.