发明名称 A MEDICAMENT FOR USE IN A METHOD OF INDUCING OR EXTENDING A CELLULAR CYTOTOXIC IMMUNE RESPONSE
摘要 The present invention relates to a medicament for use in a method of extending a cellular cytotoxic immune response against an antigen-comprising protein, the method comprising the step of: i) administering to a patient having T cells activated against an antigen a peptide-loaded major histocompatibility complex class I (MHC-I) presenting cell and an adjuvant which supports a Th-1-mediated response, wherein the peptide is derived from the antigen-comprising protein, thereby re-activating the activated T cell, wherein the peptide-loaded major histocompatibility complex class I (MHC-I) presenting cell of step i) is administered in a time frame of from 0 h to 14 days after the T cells were activated against an antigen.
申请公布号 WO2015140172(A3) 申请公布日期 2015.12.10
申请号 WO2015EP55568 申请日期 2015.03.17
申请人 BUNDESREPUBLIK DEUTSCHLAND LETZTVERTRETEN DURCH DAS ROBERT KOCH-INSTITUT VERTRETEN DURCH SEINEN PRÄSIDENTEN 发明人 KROCZEK, RICHARD
分类号 A61K39/00 主分类号 A61K39/00
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