AGENTS, KITS AND METHODS FOR COMPLEMENT FACTOR H-RELATED PROTEIN 1 DETECTION

摘要

The present invention relates to an assay for specific detection of complement factor H-related protein 1 (CFHR1) in a sample from a subject, as well as kits and agents related thereto.

主权项

1. A kit comprising
a) a first agent capable of binding complement factor H R1 (CFHR1) protein, and b) a second agent capable of binding complement factor H R1 (CFHR1) protein, wherein the first agent and the second agent bind to different and non-overlapping epitopes, and wherein the first agent and the second agent do not both crossreact with CFH, and wherein the first agent and the second agent do not both crossreact with CFHR2, and wherein the first agent and the second agent do not both crossreact with CFHR3, and wherein the first agent and the second agent do not both crossreact with CFHR4, and wherein the first agent and the second agent do not both crossreact with CFHR5, and wherein one agent is labeled with a detectable label, and wherein the other agent is capable of immobilizing on a solid phase.