| 发明名称 |
METHOD FOR PREDICTING THE ONSET OF EXTRAPYRAMIDAL SYMPTOMS (EPS) INDUCED BY AN ANTIPSYCHOTIC-BASED TREATMENT |
| 摘要 |
The invention relates to methods for predicting the onset of extrapyramidal symptoms (EPS) induced by an antipsychotic-based treatment as well as methods for providing personalized medicine to patients based on the sequence of several SNPs associated with the onset of EPS. The invention relates as well to kits for carrying out the diagnostic and predictive medicine methods. |
| 申请公布号 |
US2015354005(A1) |
申请公布日期 |
2015.12.10 |
| 申请号 |
US201414763292 |
申请日期 |
2014.01.24 |
| 申请人 |
UNIVERSITAT DE BARCELONA ;HOSPITAL CLÍNIC DE BARCELONA ;INSTITUT D' INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER ;CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED (CIBER) |
发明人 |
Mas Herrero Sergi;Gassó Astorga Patricia;Malagelada Grau Cristina;Bernardo Arroyo Miquel;Lafuente Flo Amalia |
| 分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. Method for predicting the onset of extrapyramidal symptoms (EPS) induced by an antipsychotic-based treatment in a subject, comprising
i) determining the sequence of the rs1130214, rs456998, rs7211818 and rs1053639 single nucleotide polymorphisms (SNPs) in a sample comprising genetic material from said subject, and ii) predicting the risk of said subject to develop EPS based on the sequence of said SNPs. |
| 地址 |
Barcelona ES |
