发明名称 POLYMERIC VASCULAR STENT AND IN VIVO VISUALIZATION THEREOF
摘要 This invention is directed to vascular stents that can be visualized in vivo through the use of fluorescent imaging.
申请公布号 US2015352264(A1) 申请公布日期 2015.12.10
申请号 US201414298144 申请日期 2014.06.06
申请人 Abbott Cardiovascular Systems Inc. 发明人 Fox Julia C.;Harrington Joel;Pacetti Stephen
分类号 A61L31/14;A61L31/06 主分类号 A61L31/14
代理机构 代理人
主权项 1. A vascular stent, comprising: a stent body comprising a biocompatible, biodegradable block copolymer having a structural block and a fluorescent block; or a stent body comprising a biocompatible, biodegradable block copolymer having a block with a Tg higher than 37° C. and a block having a Tg lower than room temperature, wherein the block with the Tg lower than room temperature forms a discrete amorphous phase within a matrix formed by the block with the Tg higher than 37° C., wherein a fluorescent substance is dispersed in the amorphous phase; or a stent body comprising a biocompatible, biodegradable semi-crystalline homopolymer having a Tg higher than 37° C., wherein a fluorescent substance is dispersed in the amorphous phase of the semi-crystalline polymer; or a stent body comprising a blend of at least two biocompatible, biodegradable polymers wherein on of the polymers is a semi-crystalline homopolymer and the other polymer is a copolymer, the blend of the two polymers having a Tg higher than 37° C. and wherein a fluorescent substance is dispersed in an amorphous phase of the blend; or a stent body comprising a biocompatible, biodegradable polymer wherein the stent body is coated with a layer comprising a biocompatible, biodegradable block copolymer having a structural block and a fluorescent block; or a biocompatible, biodegradable block copolymer having a block with a Tg higher than 37° C. and a block having a Tg lower than room temperature, wherein the block with the Tg lower than room temperature forms a discrete amorphous phase within a crystalline or semi-crystalline matrix formed by the block with the Tg higher than 37° C., wherein a fluorescent substance is dispersed in the amorphous phase.
地址 Santa Clara CA US