| 摘要 |
PROBLEM TO BE SOLVED: To provide micelle assemblies suitable for the delivery of therapeutic agents (including, e.g., oligonucleotides or peptides) to a living cell.SOLUTION: A micelle assembly contains a block copolymer represented by formula I. (Ato Aare -C-C-, -C(O)(C)C(O)O-, or -O(C)C(O)-; a is from 1 to 4; Yto Yare H, covalent bonds, -C1-10 alkyl,-C4-10 heteroaryl or the like; Rto Rare H, -CN, alkyl or the like; Qto Qare residues hydrophilic at a pH of 6.6 to 7.6, or positively or negatively charged residues.) |
