TISSUE PROCESSING APPARATUS WITH MIXING DEVICE AND METHOD FOR PROCESSING ADIPOSE TISSUE

摘要

A portable apparatus for collection and processing of human biological material, such as containing adipose extracted during a lipoplasty procedure, is useful for multi-step processing to prepare a concentrated product (e.g., stromal vascular fraction) or a fat graft composition. The apparatus has a container with a containment volume with a tissue retention volume and a filtrate volume separated by a filter and with a tapered portion to a collection volume for collecting concentrate product. The apparatus includes a mixing device disposed at least in part within the tissue retention volume, and wherein the mixing device has a rotatable shaft extending from outside of to inside of the internal containment volume and has at least one mixing member that is disposed in the tissue retention volume with at least a portion disposed in the tapered portion of the internal containment volume and that is connected with the shaft to move through the tissue retention volume when the shaft is rotated.

主权项

1. An apparatus useful for collection of human biological material comprising adipose and post-collection processing of collected material, the apparatus being orientable in a collection orientation, as oriented in the collection orientation the apparatus comprising:
a filter; a container having an internal containment volume, the internal containment volume comprising:
a tissue retention volume and a filtrate volume separated by the filter;a collection volume within the filtrate volume, the collection volume having a bottom elevation corresponding to a bottom elevation of the filtrate volume and a top elevation that is lower than the bottom elevation of the tissue retention volume; anda tapered portion that tapers in a downward direction with at least a portion of the tapered portion being located above the collection volume and with at least a portion of the tissue retention volume being within the tapered portion; an inlet port in fluid communication with the tissue retention volume and configured for introducing the human biological material directly into the tissue retention volume; a suction port in fluid communication with the filtrate volume and providing access to the filtrate volume for suctioning from the filtrate volume components passing through the filter from the tissue retention volume to the filtrate volume; and a mixing device disposed at least in part within the tissue retention volume for mixing contents within the tissue retention volume, wherein the mixing device comprises a rotatable shaft extending from outside of the internal containment volume to inside of the internal containment volume and comprises at least one mixing member that
is disposed in the tissue retention volume with at least a portion disposed in the tapered portion of the internal containment volume andis connected with the shaft to move through the tissue retention volume when the shaft is rotated.