| 发明名称 |
Method and constructs for the pH dependent passage of the blood-brain-barrier |
| 摘要 |
<p>Herein is reported a fusion polypeptide comprising i) at least one binding site, e.g. which comprises an antibody heavy chain variable domain and an antibody light chain variable domain, and which binds to an internalizing cell surface receptor, and ii) at least one pharmaceutically active compound, whereby the EC</p> |
| 申请公布号 |
AU2012244816(B2) |
申请公布日期 |
2015.12.10 |
| 申请号 |
AU20120244816 |
申请日期 |
2012.04.18 |
| 申请人 |
ROCHE GLYCART AG |
发明人 |
BOHRMANN, BERND;FRESKGARD, PER-OLA;HUGENMATTER, ADRIAN;KOPETZKI, ERHARD;MOESSNER, EKKEHARD;NIEWOEHNER, JENS;SADE, HADASSAH SUMUM;UMANA, PABLO |
| 分类号 |
C07K16/28 |
主分类号 |
C07K16/28 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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