摘要 |
The present invention relates to a method for diagnosing a disease, comprising the step detecting in a sample an autoantibody binding to the alpha 3 subunit of the human neuronal Na(+)/K(+) ATPase, an isolated and/or recombinant polypeptide comprising the alpha 3 subunit of the human neuronal Na(+)/K(+) ATPase, a use of a membrane-associated human Na(+)/K(+) ATPase or a variant thereof for the diagnosis of a disease, an isolated and/or recombinant polypeptide comprising the alpha 3 subunit of the human neuronal Na(+)/K(+) ATPase or a variant thereof, for use in the treatment of a disease, an autoantibody binding to said polypeptide and a method for isolating such autoantibody, a pharmaceutical composition, medical or diagnostic device or test kit comprising the polypeptide. |
申请人 |
EUROIMMUN MEDIZINISCHE LABORDIAGNOSTIKA AG |
发明人 |
SCHARF, MADELEINE, DR.;DETTMANN, INGA-MADELEINE, DR.;KOMOROWSKI, LARS, DR.;MISKE, RAMONA, DR.;PROBST, CHRISTIAN, DR.;DENNO, YVONNE;HEIDENREICH, FEDOR, PROF.DR.;GIESS, RALF, DR. |