IDENTIFICATION OF A WEST NILE VIRUS CD4 T CELL EPITOPE AND USE THEREOF
摘要
<p>Described herein is the identification and of a potent West Nile virus (WNV) CD4 positive T cell epitope and its use for increasing the immunogenicity of heterologous flavivirus vaccines, such as dengue virus type 2 (DENV-2) DNA and virus-like particle (VLP) vaccines. Also described are methods for the identification of potent T cell epitopes to enhance immunogenicity of multivalent vaccines.</p>
申请公布号
EP2731961(A4)
申请公布日期
2015.12.09
申请号
EP20120810873
申请日期
2012.07.11
申请人
THE GOVERNMENT OF THE UNITED STATES OF AMERICA ASRERESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH & HUMAN SERVICES