发明名称 |
CRYSTALLINE FORM OF LINACLOTIDE |
摘要 |
<p>Linaclotide is a guanylate cyclase type C receptor (GCC) agonist used in the treatment of gastrointestinal disorders and conditions, including irritable bowel syndrome and chronic constipation. Crystalline form II of Linaclotide is prepared in high purity and yields and shows superior chemical stability in comparison to known crystal or amorphous forms of Linaclotide. A process for the purification of Linaclotide is also provided.</p> |
申请公布号 |
EP2950803(A1) |
申请公布日期 |
2015.12.09 |
申请号 |
EP20140701563 |
申请日期 |
2014.01.28 |
申请人 |
SANDOZ AG |
发明人 |
STEFINOVIC, MARIJAN;SCANSETTI, MYRIAM;REECE, HAYLEY |
分类号 |
A61K38/10;C07K7/08 |
主分类号 |
A61K38/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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