发明名称 |
ANTI-CANCER DIBENZOCYCLOHEPTANE DERIVATIVES AND A CATALYTIC METHOD FOR DIBENZOCYCLOHEPTANE SYNTHESIS AND ALLOCOLCHICINOID SYNTHESIS |
摘要 |
In a non-limiting embodiment, there is provided a compound of formula (I), which may permit for a method or use in treating or preventing a cancer, such as pancreatic cancer or leukemia. In one embodiment, there is also provide a method of preparing a compound of formula (Ia), the method including conducting a cyclization reaction of a compound of formula (III) to obtain a compound of formula (IV), wherein conducting the cyclization reaction comprises conducting a Michael reaction in the presence of a Lewis acid. |
申请公布号 |
EP2952501(A2) |
申请公布日期 |
2015.12.09 |
申请号 |
EP20150170291 |
申请日期 |
2015.06.02 |
申请人 |
UNIVERSITY OF WINDSOR |
发明人 |
GREEN, JAMES;MEHDI, MARIAM;DJURDJEVIC, SINISA |
分类号 |
C07C69/76;C07C43/23;C07C43/295;C07C49/255;C07C231/10;C07C233/23;C07C247/14;C07D317/54;C07D317/70 |
主分类号 |
C07C69/76 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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