发明名称 |
THERAPEUTIC AGENT DELIVERY SYSTEM AND DEVICE FOR LOCALIZED APPLICATION OF THERAPEUTIC SUBSTANCES TO A BIOLOGICAL CONDUIT |
摘要 |
<p>The invention provides a system, device and method for localized application of therapeutic substances within a biological conduit. One embodiment comprises a rotational atherectomy device having a flexible, elongated, rotatable, drive shaft having a lumen and with an eccentric enlarged abrading head having at least one application hole attached therethrough and in communication with a therapeutic agent delivery sheath and an operator-controlled actuator. The therapeutic substances may then spray radially outwardly from the application hole(s) on the eccentric abrading head during and/or after high-speed rotation of the head. Another embodiment comprises compartments in the abrading head that hold therapeutic agent(s) for release during high-speed rotation. In each case, the therapeutic substance(s) is delivered with radial forces resulting from high-speed orbital rotation of the eccentric abrading head, driving the therapeutic substance(s) into the conduit wall.</p> |
申请公布号 |
EP2536341(B1) |
申请公布日期 |
2015.12.09 |
申请号 |
EP20110745130 |
申请日期 |
2011.02.16 |
申请人 |
CARDIOVASCULAR SYSTEMS, INC. |
发明人 |
SCHOENLE, VICTOR, LEO;RIVERS, JODY, LEE;DARLEY, JESSE, C. |
分类号 |
A61B17/22;A61M11/00 |
主分类号 |
A61B17/22 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|