Medical hyperspectral imaging for evaluation of tissue and tumor

摘要

Apparatus and methods for hyperspectral imaging analysis that assists in real and near-real time assessment of biological tissue condition, viability, and type, and monitoring the above over time. Embodiments of the invention are particularly useful in surgery, clinical procedures, tissue assessment, diagnostic procedures, health monitoring, and medical evaluations, especially in the detection and treatment of cancer.

主权项

1. A multispectral or hyperspectral medical imaging system comprising:
a plurality of LED lights, each respective LED light in the plurality of LED lights configured to emit radiation at a particular spectral band in a plurality of spectral bands used by a diagnostic protocol module; a first stage optic configured to receive radiation projected, from one or more respective LED lights in the plurality of LED lights, off of an in vivo tissue located at a region of interest on a subject; one or more polarizers in optical communication with the first stage optic; an imaging sensor for recording an image of the radiation projected off of the in vivo tissue; a diagnostic protocol module adapted to detect a particular characteristic of the in-vivo tissue; a diagnostic processor configured to:
switch one or more respective LED light in the plurality of LED lights off and on based on the diagnostic protocol module,instruct the imaging sensor to record a plurality of images of the region of interest based on the diagnostic protocol module, each respective image in the plurality of images corresponding to radiation emitted at a particular spectral band by one or more respective LED light in the plurality of LED lights,obtain a multispectrally or hyperspectrally resolved image based on the plurality of images, andobtain a pseudo-color image of the region of interest based on the multispectrally or hyperspectrally resolved image, the pseudo-color image enhancing the visibility of the particular characteristic of the in vivo tissue present in the region of interest; and a projection subsystem configured to project the pseudo-color image onto the region of interest, wherein the projection subsystem comprises an image projector with a field-of-view co-aligned with a field of view of the first stage optic.